Protein
Plant protein
Hevia-Larraín et al., Sports Medicine, 2021
Crimarco, Gardner et al., American Journal of Clinical Nutrition, 2020.
Phytosphere · Blueprint
Open Research in The Phytosphere™
Plants Have Superpowers™ is more than a slogan. We have an obsession — finding the remarkable nutritive benefits of plants and delivering them to you. We’ve spent nearly two decades in deep research and development with plants, and we are energized every day by what they can do. We love learning about plants. We love helping you access their special nutrition.
This page is dedicated to ongoing scientific research from around the world on plant-derived inputs and their potential impact on human health and performance. We emphasize peer-reviewed research as well as rigorous clinical trials in humans.
This is not a list of ingredients in our products. It is also not a signal that we intend to use any particular compound in future products. It is a summary of areas and studies we find interesting and think you might too — a project dedicated to open research and a community that wants to advance human understanding around the superpowers of plants.
Additional disclaimers: Not medical advice, and not a substitute for talking to a clinician. Not a product page — no product is described, recommended, or sold here. Not a claim that any listed input will produce a given result in any individual. Not a claim that any input listed here is in our products or our portfolio. Not exhaustive; studies are added as they are reviewed. For the contents of any of our individual products, consult that product’s label. Nothing on this page qualifies, extends, or substitutes for it.
Submit Compound for Review
This is an open body of exploration, and it is deliberately unfinished — we are kicking it off and calling on phytoenthusiasts from around the world. If there’s a plant compound you think belongs on the list, submit a suggestion. Useful submissions include: a description of the compound and its plant source, what you think it does, and any published human research and/or clinical trials. The more robust the data, the further it will travel in our process.
We read every submission. Promising ones go to our network of physicians, registered dietitians and nutrition researchers for an independent look at the evidence, and then potentially to our own scientific team to explore further, after which we may add it to this research page.
We can’t treat submissions as confidential, and reviewing a compound isn’t a commitment to develop it or an agreement of any kind. Please don’t send anything you consider proprietary.
Track I
Structure & Fuel
Plant protein
Hevia-Larraín et al., Sports Medicine, 2021
Crimarco, Gardner et al., American Journal of Clinical Nutrition, 2020.
Whole grains, pulses, psyllium
Carbohydrate quality and human health: a series of systematic reviews and meta-analyses
Reynolds et al., The Lancet, 2019
Oats (Avena sativa)
Cholesterol-lowering effects of oat β-glucan: a meta-analysis of randomized controlled trials
Whitehead et al., American Journal of Clinical Nutrition, 2014
Chicory root inulin & oligofructose
Reimer et al., American Journal of Clinical Nutrition, 2020
Track II
Vascular & Metabolic
Vegetable oils, nuts, seeds, grains
Continuous dose-response relationship of the LDL-cholesterol-lowering effect of phytosterol intake
Demonty et al., Journal of Nutrition, 2009
Soybeans, tofu, tempeh, edamame
Taku et al., American Journal of Clinical Nutrition, 2007
Blanco Mejia et al., Journal of Nutrition, 2019
Blueberries and dark-pigmented fruit
Curtis et al., American Journal of Clinical Nutrition, 2019
Milled flaxseed; walnuts
Potent Antihypertensive Action of Dietary Flaxseed in Hypertensive Patients
Rodriguez-Leyva et al., Hypertension (AHA), 2013
Beetroot; leafy greens
Dietary Nitrate Provides Sustained Blood Pressure Lowering in Hypertensive Patients
Kapil et al., Hypertension (AHA), 2015
Chlorophyll’s core mineral (greens, legumes, seeds)
Zhang et al., Hypertension (AHA), 2016
Fruit, vegetables, legumes, tubers
Track III
Brain, Eye & Cellular Energy
Microalgal oil
Beneficial effects of docosahexaenoic acid on cognition in age-related cognitive decline
Yurko-Mauro et al., Alzheimer’s & Dementia, 2010
Marigold; leafy greens
Lutein + Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration
AREDS2 Research Group, JAMA, 2013
AREDS2 Report 28, JAMA Ophthalmology, 2022
Gut metabolite of pomegranate, walnut & berry ellagitannins
Liu et al., JAMA Network Open, 2022
Higher spermidine intake is linked to lower mortality: a prospective population-based study
Kiechl et al., American Journal of Clinical Nutrition, 2018
Mushrooms, tempeh, garlic (fungal-derived)
Ergothioneine is associated with reduced mortality and decreased risk of cardiovascular disease
Smith et al., Heart, 2020
Track IV
Defense & Adaptation
Broccoli sprouts — released from glucoraphanin on chewing
Egner et al., Cancer Prevention Research (AACR), 2014
Journal of the American Academy of Dermatology, 2019
Kohli et al., JAAD, 2017